DNA is a molecule that contains the genetic instructions used in the development and function of all known living organisms and many viruses. These instructions are stored as a code made up of four chemical bases: adenine (A), thymine (T), cytosine (C), and guanine (G). The code specifies the sequence of the building blocks, called nucleotides, of DNA. During replication, these nucleotides are combined in pairs to form the rungs of the DNA ladder. The order of these pairs, A with T and C with G, creates the genetic code, which determines the sequence of amino acids in proteins.
DNA: The Molecule of Life
DNA is a double helix molecule that contains the genetic instructions used in the development and function of all living organisms. The name deoxyribonucleic acid is derived from the fact that it consists of a sugar (deoxyribose), a phosphate group, and nitrogenous bases. The four types of nitrogenous bases are adenine (A), thymine (T), cytosine (C), and guanine (G). The sequence of these bases forms the genetic code, which dictates the function of every protein in the body.
DNA is located in the nucleus of cells and is passed down from generation to generation. It is responsible for the transmission of hereditary information and the variation of characteristics within a species. Every living organism has DNA, including bacteria, plants, and animals.
The discovery of the structure of DNA by James Watson and Francis Crick in 1953 revolutionized the field of biology. Their work led to a greater understanding of the role DNA plays in the function of living organisms. Today, DNA sequencing is used to diagnose genetic disorders, identify individuals for forensic purposes, and study the evolution of life on Earth.
The Structure of DNA
Deoxyribonucleic acid or DNA is a molecule that carries the genetic instructions used in the development and function of all known living organisms and many viruses. DNA and ribonucleic acid (RNA) are nucleic acids; alongside proteins, lipids and complex carbohydrates (polysaccharides), they are one of the four major types of macromolecules that are essential for all known forms of life. Most DNA molecules consist of two biopolymer strands coiled around each other to form a double helix. The two DNA strands are called polynucleotides since they are composed of simpler monomer units called nucleotides. Each nucleotide is composed of one of four nitrogen-containing nucleobases (cytosine [C], guanine [G], adenine [A] or thymine [T]), a sugar called deoxyribose, and a phosphate group. The nucleotides are joined to one another in a chain by covalent bonds between the sugar of one nucleotide and the phosphate of the next, resulting in an alternating sugar-phosphate backbone.
The nitrogenous bases of the two separate polynucleotide strands are bound together, according to base pairing rules (A with T, and C with G), with hydrogen bonds to make double-stranded DNA. The total amount of base pairs in a given DNA sample is the base pair count. The DNA base pairs are divided into two groups, pyrimidines and purines. In DNA, the pyrimidines are thymine and cytosine; the purines are adenine and guanine.
DNA is a long polymer made from repeating units called nucleotides. The structure of DNA is dynamic along its length, being capable of coiling into tight loops, and other shapes. In all species, it is composed of two helical chains, bound to each other by hydrogen bonds. Both chains are.
The Function of DNA
DNA is the hereditary material in humans and almost all other organisms. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).
The information in DNA is stored as a code made up of four chemical bases: adenine (A), thymine (T), cytosine (C), and guanine (G). Human DNA consists of about 3 billion bases, and more than 99 percent of those bases are the same in all people. The order of the bases determines the information available for building and maintaining an organism.
DNA bases pair up with each other, A with T and C with G, to form units called base pairs. Each base is also attached to a sugar molecule and a phosphate molecule. Together, a base, sugar, and phosphate are called a nucleotide. Nucleotides are arranged in two long strands that form a spiral called a double helix. The structure of the double helix is somewhat like a ladder, with the base pairs forming the rungs and the sugar-phosphate backbones making up the sides of the ladder.
DNA is responsible for the genetic information within cells. This information is used to direct the synthesis of proteins, which are the building blocks of all cells and perform most of the work in the body. DNA is passed from generation to generation, providing the instructions for an organism’s development and function.